Aso, Takeshi, et al. «A Pure S-equol Complement Alleviates Sizzling Flushes and Different Menopausal Signs in Equol Nonproducing Postmenopausal Japanese Ladies.» Journal of Girls’s Well being (2002), vol. 21, no. 1, 2012, pp. 92-100.
Aso T, Uchiyama S, Matsumura Y, et al. A natural S-equol complement alleviates sizzling flushes and other menopausal signs in equol nonproducing postmenopausal Japanese ladies. J Womens Well being (Larchmt). 2012;21(1):92-100.
Aso, T., Uchiyama, S., Matsumura, Y., Taguchi, M., Nozaki, M., Takamatsu, Okay., Ishizuka, B., Kubota, T., Mizunuma, H., & Ohta, H. (2012). A natural S-equol complement alleviates sizzling flushes and other menopausal signs in equol nonproducing postmenopausal Japanese ladies. Journal of Women’s Well being (2002), 21(1), 92-100. https://doi.org/10.1089/jwh.2011.2753
Aso T, et al. A Pure S-equol Complement Alleviates Scorching Flushes and Other Menopausal Symptoms in Equol Nonproducing Postmenopausal Japanese Ladies. J Womens Well being (Larchmt). 2012;21(1):92-100. PubMed PMID: 21992596.
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TY — JOUR T1 — A pure S-equol supplement alleviates scorching flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese ladies. AU — Aso,Takeshi, AU — Uchiyama,Shigeto, AU — Matsumura,Yasuhiro, AU — Taguchi,Makoto, AU — Nozaki,Masahiro, AU — Takamatsu,Kiyoshi, AU — Ishizuka,Bunpei, AU — Kubota,Toshiro, AU — Mizunuma,Hideki, AU — Ohta,Hiroaki, Y1 — 2011/10/12/ PY — 2011/10/14/entrez PY — 2011/10/14/pubmed PY — 2012/5/24/medline SP — 92 EP — one hundred JF — Journal of women’s health (2002) JO — J Womens Health (Larchmt) VL — 21 IS — 1 N2 — Goal: The target of this clinical trial was to study the efficacy of a complement containing natural S-(-)equol, a daidzein metabolite, in reducing menopausal signs. Methods: On this multicenter, double-blind placebo-managed trial, 160 equol nonproducing, postmenopausal Japanese women who experienced at the very least 1 sizzling flush/day have been randomly assigned to eat 10 mg/day S-(-)equol (n=77 ladies) or placebo (n=83 ladies) for 12 weeks. Members accomplished a standardized menopausal symptom checklist and rated 5 frequent menopause signs by a visible analog scale at baseline, week 12, and week 18 (6-week postintervention). Physical, blood, and urine examinations have been carried out. One hundred twenty-six women accomplished the research. Outcomes: At baseline, daily scorching flush frequency was 2.9±2.1 for the S-(-)equol group and 3.2±2.4 for the placebo group. After the 12-week intervention, the S-(-)equol group had a larger lower from baseline in sizzling flush frequency compared with the placebo group (-1.9±1.8/day, -58.7%, vs. -1.0±2.0/day, -34.5%, p=0.009). The severity of scorching flushes and neck or shoulder muscle stiffness considerably decreased in the S-(-)equol group compared with the placebo group. No modifications in clinical parameters or serious adversarial results were reported. CONCLUSIONS: This is the first trial to point out beneficial results of a 10-mg natural S-(-)equol complement consumed each day for エクオール（及びエクオール サプリ） 12 weeks on main menopausal signs, particularly, scorching flushes and neck or shoulder muscle stiffness, in postmenopausal Japanese girls. This supplement affords a promising different for management of menopausal symptoms.